Single-step Synthesis and Characterization of Zr-MOF onto Wool Fabric: Preparation of Antibacterial Wound Dressing with High Absorption Capacity

Improvement of curative herbal extracts effectiveness through novel drug delivery systems is a field study for the researches nowadays. Zirconium-based metal-organic frameworks (Zr-MOFs) are one most capable porous nanocarriers that need biocompatible template to be used in biomedical applications. In this work, Zr-MOF was synthesized into wool fabric in-situ one-pot method with different molar ratios. The final fabrics were characterized thoroughly using various techniques and effect components on monodispersity nucleation tendency onto surface explained. resultant stablished absolute wash durability, increased air-permeability up twice reasonable hydrophilicity. Tensile strength young modulus decreased 30 1244 % strain 66 %. Salvia Officinalis (SO) Calendula (CO) loaded modified 1154 1842 absorption capacity. release profiles showed domination diffusion mechanism. wool-MOF-SO CO displayed both 100 antibacterial activity against Escherichia coli 60.95 64.64 Staphylococcus aureus because diverse components. proved biocompatibility human skin however exhibited high toxicity.